Miss Nancy Quayle raised £220 by baking delicious cakes to sell at her recent cake stall for the Foundation and a photo of which was in the Lancashire Evening Post.

Mr Kevan Dean raised £500 by walking to the top of Pen-y-ghent when fully recovered from Neurosurgery and E. Surveyers matched funded, so a total of £1,000 was given.

Mr & Mrs Rick Cookson held an informal buffet charity evening at Lytham Green Drive Golf Club and raised £500 for the Foundation.

Mr & Mrs Scott Deakin held a fund raising event at the Masonic Hall in Barrow in Furness in which £8,756.00 was raised including the donation from Sellafield Ltd.

Mr & Mrs Mark Beverley held the Beverley Ball in Wigton Cumbria and organised many other activities in Cumbria and Lancashire, they raised £27,018.84 for the Foundation.



You can help to ensure the continuation of this valuable work by making a financial contribution to the Foundation.

Even the smallest donation is welcome.

Patient helped by nurse nurses helping patient.

Please help us by:

CASH — giving a cash payment in a sealed envelope, addressed to your Consultant in charge and marked S.D.N.F.
CHEQUES — cheques made payable to S.D.N.F. and sent to your Consultant in charge, c/o Depatment of Neuroscience, Royal Preston Hospital, Sharoe Green Lane PRESTON PR2 4HT.
GIFT AID — by covenanting a fixed sum annually to the Department of Neuroscience, whereby we will be able to reclaim the income tax and so increase the value of the gift. We will supply a form of covenant on request, or download a form.
FUND-RAISING —  holding a fund raising event which will not only raise money but will also highlight the work of the Foundation.

IF you want to find out more, or need a more direct approach you can contact Jan Winnard, SDNF Trustee by email - This email address is being protected from spambots. You need JavaScript enabled to view it.

Why we need your help

The Foundation is based at the Department of Neuroscience in Preston, which serves a population of approximately 2 million people in the Health Districts of Preston, Chorley, South Ribble, Blackpool, Blackburn, Burnley, Lancaster and South Cumbria. Each year the Department cares for more than 2000 inpatients and more than 5000 outpatients.

T 5 1

We have achieved a great deal in the treatment of; Head injuries, brain and spinal tumours, strokes, cerebral haemorrage, multiple sclerosis, motor neurone disease and Parkinson’s disease.

The cost of providing this excellent service is enormous.

Sadly, there is very little available from Government or State funding to spend on Education and Research.

If the Department is to continue its pioneering work at the frontiers of the Neurosciences, it must maintain and expand its research and training facilities.


 To download our donation form for Gift Aid, please click on the button below.


The Annual Lecture is held in May every year in the Health Academy 1 (previously Education Centre 1) at Lancashire Teaching Hospitals NHS Foundation Trust, Royal Preston Hospital site, when a prominent Neuroscientist is invited to deliver a lecture to an audience of medical practitioners from the North West. 

The lectures have become a landmark in the scientific programme of the medical community. 



2021 - Professor Mayank Goyal - Prof of Radiology and Clinical Neurosciences, Calgary. Held via Zoom due to the ongoing Covid-19 Pandemic.

'Endovascular Frontiers for Acute Stroke'

2020 - No Annual Lecture held due to the Covid-19 Pandemic

2019 - Baroness Susan Greenfield - Research Scientist, Oxford. 

 'A Neuroscientific perspective on Consciousness'

2018 - Professor James T. Goodrich - Prof of Neurosurgical Surgery, Paediatrics, Plastic and Reconstructive Surgery, New York, USA

'Conjoint Twins'

2017 - Professor John Darling - Prof of Neuro-oncology, Wolverhampton

'Brain Cancer - how long until biology provides new therapies?'

2016 - Professor Tim Solomon - Prof of Neurology, University of Liverpool

'Neurological Infections. Locally, Nationally and Internationally'

2015 - Professor Sir Graham Teasdale - Retired Prof of Neurosurgery, Glasgow

'Glasgow Coma Scale - past, present and future'

2014 - Professor Colin Blakemore - Prof of Neuroscience and Philosopjy, London -

'Vision Impossible'

2013 - Professor Laurent Spelle, MD, PhD, Professor of Neuroradiology, Beaujon Hospital Paris

The 'Role of Endovascular Interventions in Vascular Conditions of the Brain'


Previous Sponsors

2021 - No Sponsors due to being held over Zoom

2020 - No Sponsors due to no Annual Lecture

2019 - Severnhealth Care, Integra Codman

2018 - Sevenhealth Care, Nevro, Depuy Synthes

2017 - Severn Health Care, Cryolife

2016 - Biogen, Stryker, Severn Health Care

2015 - BBraun, Codman, Severn Health Care, Cryolife, Brainlab

2014 - Tissuemed, Codman, Stryker

2013 - Microvention UK

2012  UCB Pharma, Microvention

2011 Eli Lilley

2010 Zimmer-Spine

2003 - 2009  Teva Pharmaceuticals (Excluding 2007)

2002 Teva Pharmaceuticals, Britannia Pharmaceuticals, UCB Pharma

2001 Shearing Healthcare, Pharmacia & Upjohn, Novartis, Britannia Pharmaceuticals, Ipsen

2000 Leica Microsystems Ltd

1999 Zeneca Pharmaceuticals Ltd, Glaxo, Britannia Pharmaceuticals Ltd, Smith Kline Beecham,
         Leica Microsystems UK L td, Rhone Poulenc Rorer, Elan Pharmaceuticals Ltd

1998 Smith, Kline & Beecham, Pharmacia & Upjohn, Parke Davis

1996 Speywood Pharmaceuticals Ltd




The Library is located on Ward 2A of Royal Preston Hospital and offers a range of library resources such as books and journals (both print and electronic) pertaining to the Neurosciences. We encourage the Neurosciences Medical and Nursing staff to use the Library as much as possible. We are building up our collections of resources so as to meet the increasing needs of our users. All library resources are for reference use only. A computer and study area are also available for research purposes. Please contact the librarian for further enquiries.

Librarian Contact Details
Address: Ward 2A
Department of Neuroscience
Royal Preston Hospital
Sharoe Green Lane North
Preston PR2 9HT
Part-time Voluntary Librarian:Christine Hughes
Working Hours: Tuesday 9am - 1pm.

1. Brain Tumour North West Tissue Bank

The Brain Tumour North West (BTNW) Tissue Bank

The Brain Tumour North West (BTNW) Tissue Bank plays a major role in NW regional neuro-oncology research collaboration. Providing researchers access to tumour tissue and blood samples is central to advancing the understanding of tumour development and testing potential treatments.

It is testament to the generosity of our patients and their relatives at such a difficult time in their lives, that they overwhelming support the collection of this tissue for research purposes.

The BTNW bank has the approval of the National Research Ethics Service as a Research Tissue Bank and is held under a Human Tissue Authority licence at Lancashire Teaching Hospitals NHS Trust in Preston.

The SDNF generously provide funding for the technical and administrative support to run this project. This priceless resource encourages new researchers into the field, builds upon basic research themes and allows their translation into better diagnostic strategies and treatments.

2. Brain Cancer - Glioblastoma Multiforme

Sydney Driscoll Abstract - Chris Sherer (June 2012)

Cancer is one of the biggest killers internationally, and brain tumours in particular strike largely independent of age, race, sex or lifestyle. Glioblastoma multiforme is the most aggressive form of brain tumour, and typically carries with it a poor prognosis.

Figure – The structure of indole (left), 223α (centre) and 209 (right)

In attempts to overcome the low quality of life and poor prognosis of glioma patients, we are grateful to the Sydney Driscoll Neuroscience Foundation and Brain Tumour North West for funding to support a PhD project aimed at making new drugs to potentially treat this disease.

The privileged structure of the indole nucleus (Fig 1) has been described as 'one of the most ubiquitous heterocyclic structures found in nature'.[1] Due to its planarity, small size and rigidity, the indole nucleus makes an ideal scaffold on which to attach functionality and thus create highly specialised drugs.

This project continues the development of two compounds that have previously been identified as having anticancer activity against glioblastoma cell lines (Fig. 1). 223α is a derivative of indole-3-carbinol, an indole-containing compound whose anti-cancer activity has been known for over 30 years, yet has only recently been shown to be active against glioblastoma cell lines by the Snape group.[2] Compound 209 is a novel compound found by the Snape group to also be active against glioblastoma cell lines.[2]

The versatile Truce-Smiles rearrangement, which has been developed by the Snape group to access a wide range of indoles, will be one of the many reactions used to synthesise a wide range of 223α and 209 derivatives. These derivatives will then be tested in preclinical studies, using colorimetric cell toxicity assays, to try and discern structure-activity relationships for both classes of compounds against a variety of established glioma cell lines and short term cultures. This will hopefully lead to a small series of highly active and rationally designed compounds that can be put forward as potential drug candidates.

[1] D. A. Horton, G. T. Bourne, M. L. Smythe, Chem. Rev. 2003, 103, 893-930.

[2] S. Prabhu, Z. Akbar, F. Harris, K. Karakoula, R. Lea, F. Rowther, T. Warr, T. Snape, Bioorg. Med. Chem. 2013, 21, 1918-1924.

3. "Arterial Spin Labelling Reveals Prolonged Arterial Arrival Time In Idiopathic Parkinson's Disease"

The current Trustees are as follows:

  • Nihal Gurusinghe – Consultant Neurosurgeon, RPH
  • Andrew Ferguson – Solicitor
  • Jan Winnard – Lecturer and Teacher Educator
  • Nick Park - Consultant Neurosurgeon, RPH